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Tag Archives: psilocybin
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Psilocybin and Psilocin: How Magic Mushrooms Work
March 23, 2026
The Science Behind the Magic — Psilocybin and Psilocin Explained
Magic mushrooms make you see the world differently. But what, exactly, causes that? The two main active compounds in magic mushrooms are psilocybin and psilocin — a pair of naturally occurring tryptamines that interact with your brain in a surprisingly elegant way.
In this guide, we break down what these substances are, how your body processes them, what they do in the brain, and what the latest science says about their safety.
A complete guide to psilocybin fungi — what they are, how they work, and why they exist.
Magic mushrooms are fungi that naturally produce the psychedelic compound psilocybin. When you eat them, your body converts psilocybin into psilocin. Psilocin then binds to serotonin receptors in the brain – especially the 5-HT2A receptor – and temporarily changes how you perceive the world, process emotions, and experience your sense of self. Scientists have identified over 200 species of psilocybin-containing mushrooms, spread across several genera. The most well-known is Psilocybe cubensis, which is the species you will find in most grow kits today.
Published March 18, 2026 · 6 min read
A landmark JAMA study published on March 10, 2026 provides the first causal evidence that Oregon psilocybin decriminalization directly increased use. In Oregon — the first US state to decriminalize magic mushrooms — roughly 90,000 additional people used psilocybin each year after Measure 110. As a result, the findings carry major implications for drug policy worldwide.
Germany — Psilocybin Therapy | Updated March 2026
Germany has approved the first psilocybin therapy Compassionate Use programme in the EU — offering a supervised clinical pathway for people with treatment-resistant depression who have run out of options.
In this article, we explain what this psilocybin therapy programme involves, who it is for, and what the research shows so far.
Can psilocybin treat OCD? A groundbreaking Yale University study says yes — and the results are remarkable. In this first-ever randomized, placebo-controlled trial, just one dose of psilocybin — the psychoactive compound in magic mushrooms — reduced obsessive-compulsive disorder symptoms within 48 hours. Even more striking, the benefits lasted for months. For the millions of people living with treatment-resistant OCD, this psilocybin OCD research opens an entirely new door.
What Is Microdosing? The Complete Guide to Microdosing Psilocybin
January 17, 2026
Microdosing is the practice of taking very small, sub-perceptual amounts of a psychedelic substance like psilocybin. You will not trip or hallucinate. Instead, you may notice subtle shifts in mood, focus, and creativity over time. Once a niche practice in Silicon Valley, microdosing has grown into a global movement. Science is finally catching up with what thousands of people have been reporting for years.
Albert Hofmann — Father of LSD and Pioneer of Psilocybin
September 12, 2023
Albert Hofmann is a name that echoes through the history of science — and through the minds of everyone who has ever felt curious about consciousness. Born on January 11, 1906, in Baden, Switzerland, this quiet, meticulous chemist became the Father of LSD — and, as we now know, so much more. His discoveries didn't just reshape chemistry. They opened a conversation that the world is still having today.
Why Grow Your Own Magic Mushrooms
August 31, 2023
Growing your own psychedelic mushrooms can be a transformative and enlightening experience. By taking control of the cultivation process, you can better ensure the quality, purity, and potency of the mushrooms you consume. Plus, it lets you form a unique connection with your fungi friends, right from the very beginning.
Here are some of the top reasons to grow your own magic mushrooms.
Terence McKenna: The Godfather of Psychedelic Culture
April 6, 2023
Writer, lecturer, ethnobotanist, psychonaut, mystic — Terence McKenna remains one of the most influential figures in the history of psychedelic culture. He spent his life advocating for the exploration of altered states of mind, building the foundations of modern shamanism, and giving counterculture an articulate, poetic voice. More than 25 years after his death, Terence McKenna's ideas continue to shape how millions of people think about consciousness, psilocybin, and the human mind.
Yoga and Psychedelics: How Breathwork and Meditation Deepen the Experience
September 24, 2021
The Intersection of Yoga, Meditation, Breathwork, and Psychedelics (2026 Update)
Yoga and psychedelics might seem like an unusual pairing at first. One is a 5,000-year-old practice of breath, body, and mind. The other involves substances that alter consciousness. Yet these two worlds share more common ground than most people realise. In recent years, the conversation between yoga and psychedelics has grown fast. This guide explores what they share, how they complement each other, and how practitioners combine them with care and intention.
